Psoriasis - Treatments

15 min readEvidence-linked topicGreen Medicine Encyclopedia

These Substances may Alleviate Psoriasis

Alcohols

 Glycerol (applied topically) may alleviate Psoriasis.  [1]

 

Alkaloids

 Allantoin (ointment applied topically) may alleviate Psoriasis.  [2]

 Berbamine may inhibit the excessive differentiation of Keratinocytes that is associated with Psoriasis.  [3]

 Berberine may inhibit the excessive differentiation of Keratinocytes that is associated with Psoriasis.  [4]

 Capsaicin (0.025% cream applied topically) may reduce the Itching, scaling, thickness and redness associated with Psoriasis.  [5]

 Oxycanthine may inhibit the excessive differentiation of Keratinocytes that is associated with Psoriasis.  [6]

 

Amino Acids

 Cysteine may improve the condition of Psoriasis patients.  [7]

 

Bile Acids

 Ursodeoxycholic Acid may alleviate Psoriasis.  [8]

 

Carbohydrates

 Chondroitin Sulfate (800 mg per day) may improve the condition of Psoriasis patients.  [9]

 

Enzymes

 Psoriasis patients often have very low levels of Glutathione Peroxidase and increasing Glutathione Peroxidase levels may alleviate Psoriasis (by inhibiting the Lipoxygenase enzyme that catalyses the formation of inflammatory Series 4 Leukotrienes that are implicated in Psoriasis).  [10]

 

Hormones

 Melatonin may be useful for the treatment of Psoriasis.  [11]

 Pregnenolone (50 - 600 mg per day) may be of some benefit to Psoriasis patients.  [12]

 Progesterone (cream applied topically) may alleviate some cases of Psoriasis.  [13]

 

Immune System Chemicals

 IgA is speculated to play a role in the prevention of Psoriasis (this is based on a case of Psoriasis in which the patient exhibited absolute IgA deficiency).  [14]

 

Lipids

 Alkylglycerols (400 mg per day) may alleviate Psoriasis (by helping to reduce the excessive proliferation of Skin Cells that occurs in Psoriasis patients and by enhancing the function of the Immune System in a way that benefits Psoriasis patients).  [15]

 Psoriasis may occur as a result of Alpha-Linolenic Acid (LNA) deficiency - Psoriasis patients are often found to be deficient in LNA.  [16]

 Cetyl Myristoleate (cream applied topically) may be useful for the treatment of Psoriasis.  [17]

 Forskolin (a Diterpene present in Coleus) may be an effective treatment for Psoriasis (Psoriasis is characterized by a relative decrease of the Second Messenger, Cyclic AMP (cAMP) in relation to Cyclic GMP (cGMP) - Forskolin counteracts this imbalance by stimulating cAMP production and activity).  [18]

 Psoriasis may occur as a result of Linoleic Acid (LA) deficiency - Psoriasis patients are often deficient in Linoleic Acid.  [19]

 Omega-3 Fatty Acids may alleviate Psoriasis:  [20]

 Docosahexaenoic Acid (DHA - 1,200 mg per day) and Eicosapentaenoic Acid (EPA - 1,800 mg per day) may decrease the redness, itching, and scaling of Psoriasis and may diminish the area affected by Psoriasis.  [21]

 EPA (applied topically) may cause significant improvement in the condition of Psoriasis patients.

 Sarsaponin (an ingredient in Sarsaparilla) may alleviate the symptoms of Psoriasis (by binding to Endotoxins that are believed to be implicated in Psoriasis): 

 Clinical trials have demonstrated that Sarsaponin significantly improves the condition of 62% of Psoriasis patients and results in complete clearance in a further 18% of Psoriasis patients.

 

Minerals

 Iron Phosphate may reduce the Skin inflammation associated with Psoriasis.

 Many Psoriais patients are found to have extremely low plasma Nickel levels (this indicates that increasing the dietary Nickel intake may be beneficial for Psoriasis patients).  [22]

 Potassium Sulfate may reduce the scaling tendency that is a characteristic of Psoriasis. 

 Selenium may alleviate Psoriasis by activating the Glutathione Peroxidase enzyme.  [23]

 Silicon may alleviate Psoriasis. 

 Silver (Mild Silver Protein form applied topically) may be useful for the treatment of Psoriasis.  [24]

 Sulfur may alleviate Psoriasis.  [25]

 Plasma Zinc levels are often lower in Psoriasis patients than in non-afflicted persons:  [26]

 Zinc Pyrithione (applied topically) may alleviate Psoriasis.

 

Organic Acids

 Alpha-Hydroxy Acids (AHAs) (applied topically) may reduce the severity of Psoriasis.  [27]

 Fumaric Acid (1% - 3% solution applied topically in conjunction with oral administration of 240 mg - 720 mg per day) may be an effective treatment for many cases of Psoriasis (caution is warranted as this treatment causes some side effects).  [28]

 Psoriasis patients have a metabolic defect that interferes with their natural production of Fumaric Acid and this defect may contribute to the development of Psoriasis.

 Orotic Acid (300 – 1,000 mg per day of Calcium Orotate) may alleviate Psoriasis.  [29]

 Salicylic Acid (2 - 3% solution applied topically by a dermatologist) is sometimes employed to remove the superfluous Skin Cells that accumulate as a result of Psoriasis. 

 

Prescribed Medications

 Bupropion may alleviate Psoriasis.  [30]

 Cyclosporine may be prescribed for the treatment of severe Psoriasis.

 Hydroxyurea may alleviate Psoriasis.  [31]

   Methotrexate (administered orally in low doses) is commonly utilized in the treatment of Psoriasis (it works by inhibiting the reproduction of cells - excessive production of Skin cells are the underlying cause of Psoriasis:  [32]

Keep reading Psoriasis - Treatments

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  • Proteins
  • Quinones
  • Second Messengers
  • Skin Improvers
  • Sulfuric Compounds
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