N-Acetyl-Cysteine

9 min readEvidence-linked topicGreen Medicine Encyclopedia

Overview

N-Acetyl-Cysteine, NAC, is an endogenous form of Cysteine produced from Cysteine within the body and also widely regarded as the preferred and more effective form of Cysteine for supplementation. 

N-Acetyl-Cysteine may Enhance the Function of these Substances

Amino Acids

 NAC increases intracellular Cysteine levels (this intracellular Cysteine is then incorporated into Glutathione) - NAC “reduces” Cystine to form Cysteine.  [1]

 NAC may prevent the destruction of Glutathione by preventing the oxidation of Glutathione.  [2]

Enzymes

 NAC may enhance the activity of Glutathione-S-Transferase.  [3]

Immune System Chemicals

 NAC may enhance the ability of Interleukin 2 (IL-2) to counteract Cancer.  [4]

Nucleic Compounds

 NAC may help to protect the body’s endogenous Deoxyribonucleic Acid (DNA) from damage.  [5]

Patented Medicines

 NAC may increase the effectiveness of Clomiphene.  [6]

 NAC may enhance the effectiveness of exogenous (pharmaceutical) Interferon Alpha in the treatment of Hepatitis C.  [7]

 NAC may enhance the effectiveness of Oseltamivir for the treatment of Influenza.  [8]

 NAC may increase the effectiveness of Ribavirin.  [9]

N-Acetyl-Cysteine may inhibit these Potentially Toxic Substances

Alcohols

 NAC may reduce the toxicity of Methanol in the Brain.  [10]

Aldehydes

 NAC binds to Acetaldehyde and may reduce the toxicity of Acetaldehyde.  [11]

 NAC may reduce the ability of Acrolein to suppress the Immune System.  [12]

Amino Acids

 NAC may inhibit the excitotoxic effects of Glutamic Acid.  [13]

 NAC may lower elevated Homocysteine levels.  [14]

Carbohydrates

 NAC may inhibit the ability of Fructose to increase Blood Pressure and cause Insulin Resistance.  [15]

 N-Acetyl-Cysteine (NAC) may help to prevent many of the toxic effects associated with Sucrose (including Obesity, increased Triglycerides, increased Blood Sugar, and increased Cholesterol).  [16]

Electromagnetic Radiation

 NAC may inhibit the ability of Ultra-Violet Radiation to activate Elastase and may hinder the ability of UV to damage the body’s Deoxyribonucleic Acid (DNA).  [17]

 NAC may inhibit the ability of UV-A to damage the body’s Deoxyribonucleic Acid (DNA).  [18]

 NAC may inhibit the ability of UV-B to damage the body’s Deoxyribonucleic Acid (DNA).  [19]

 NAC may protect the body from the toxic effects of exposure to Gamma-Rays.  [20]

Environmental Toxins

 NAC may counteract the toxicity of Chloroform.  [21]

Enzymes

 NAC may inhibit the ability of Ultra-Violet Radiation to activate Elastase.  [22]

 NAC may inhibit the activity of Ornithine Decarboxylase.  [23]

Immune System Chemicals

 NAC may lower elevated Interleukin 1 levels.

 NAC may lower elevated Interleukin 6 levels.

 NAC may retard the ability of Tumor Necrosis Factor (TNF) to inhibit the maturation of Oligodendroglia and may lower elevated TNF levels.  [24]

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