Deoxyribonucleic Acid
Overview
Deoxyribonucleic Acid, DNA, is a type of Polynucleotide Nucleic Acid that resides in the Mitochondria and Nuclei of all of the body's Cells.
Biological Functions of Endogenous DNA
The formation of life itself depends upon the proper translation of the original genetic code contained within DNA.
The continuity of DNA code is ensured by repair processes and by DNA replication.
Aging Process
Cellular Aging Process has been attributed to errors that occur during DNA repair and replication. [1]
Cells
DNA is an essential component of all new healthy Cells of the body.
Immune System
Abnormal DNA synthesis may be implicated in Cancer:
DNA is (in addition to being an essential component of all new healthy Cells) is an essential constituent of Cancer Cells - some Antimetabolite Anti-Cancer Pharmaceuticals attempt to prevent further growth of Cancer Cells by preventing the conversion of Folic Acid to its active Folinic Acid form which is essential for the endogenous production of DNA.
Proteins
DNA carries the instructions for the synthesis of Proteins - Endogenous from Amino Acids.
Sexual System
DNA is essential for the transmission of hereditary characteristics to offspring (due to DNA being an essential component of Chromosomes).
Health Benefits of Dietary (Exogenous) DNA
Aging & Life Extension
Dietary DNA may possess Life Extension potential: [2]
Although evidence for this claim is scant, in one study rats injected with supplemental Nucleic Acids lived for twice as long as control subjects.
Cardiovascular System
Megaloblastic Anemia may occur as a result of DNA deficiency.
Organic Acids
DNA increases the synthesis of endogenous Uric Acid.
Health Benefits of Microdose DNA
Ears & Hearing
DNA (microdose DNA therapy administered sublingually) may be useful for the treatment of Otitis Media. [3]
Respiratory System
DNA (microdose DNA therapy administered sublingually) may be useful for the treatment of Chronic Obstructory Pulmonary Disease (COPD): [4]
DNA (microdose DNA therapy administered sublingually) may be useful for the treatment of Asthma. [5]
DNA (microdose DNA therapy administered sublingually) may be useful for the treatment of (chronic) Bronchitis. [6]
DNA (microdose DNA therapy administered sublingually) may be useful for the treatment of the Common Cold. [7]
DNA (microdose DNA therapy administered sublingually) may be useful for the treatment of Cystic Fibrosis. [8]
These Substances may Enhance the Synthesis of Endogenous DNA
Amino Acids
Glutamine supplies the necessary Nitrogen atom for the manufacture of endogenous DNA.
Orotic Acid may be essential for the synthesis of endogenous DNA (due to its role as an intermediate in the synthesis of Pyrimidine Nucleotides).
S-Adenosylmethionine (SAMe) is essential for the production of DNA (SAM functions as a for DNA). [9]
Carbohydrates
Ribose is a component of DNA. [10]
Enzymes
Deoxyribonuclease (a Nuclease) splits DNA at specific places in the DNA molecule and is the catalyst for the hydrolysis (breakdown) of DNA into its individual Nucleotides.
DNA Polymerase catalyzes the production and replication of DNA by linking individual Nucleotides into the "unzipped" DNA molecule (a Polynucleotide).
Poly(ADP-ribose)polymerase (PARP) is involved in the generalized excision-repair pathway, which is essential for repairing damaged Deoxyribonucleic Acid (DNA).
Minerals
Magnesium may facilitate the production and utilization of endogenous DNA. [11]
Selenium (especially the L-Selenomethionine form) may facilitate the of endogenous DNA. [12]
Zinc may assist the enzyme that produces DNA. [13]
Proteins
Lactoferrin may facilitate the endogenous production of DNA. [14]
Vitamins
Choline may be essential for the synthesis of endogenous DNA. [15]
Folic Acid is a cofactor for the synthesis of endogenous DNA and is required for the incorporation of Uracil into DNA. [16]
Vitamin A may be essential for the synthesis of endogenous DNA.
Vitamin B6 may be essential for the synthesis of endogenous DNA. [17]
Vitamin B12 may be essential for the synthesis of endogenous DNA. [18]
Vitamin E may be essential for the synthesis of endogenous DNA. [19]
These Substances may Protect the Body’s Endogenous DNA
Alkaloids
The Trimethylglycine (TMG) form of Betaine may help to protect the body’s cellular DNA from damage (by functioning as a methyl donor). [20]
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