Acetyl-L-Carnitine

6 min readEvidence-linked topicGreen Medicine Encyclopedia

Overview

Acetyl-L-Carnitine, ALC, functions as an antioxidant and promotes the production of glutathione. ALC can increase mitochondrial energy production in all cells, boosting physical and mental energy. Studies indicate that ALC can be beneficial in treating Alzheimer's dementia, elderly people suffering from depression, diabetic neuropathies, and cognitive impairment from alcoholism. The principal dietary source of acetyl-L-carnitine is red meat. Supplemental Acetyl-L-Carnitine should be kept refrigerated to maintain its potency.

 Acetyl-L-Carnitine - Health Benefits

Acetyl-L-Carnitine may Enhance the Function of these Substances

Amino Acids

 ALC increases tissue levels of Carnitine.

Enzymes

 ALC may stimulate the activity of Alpha-Secretase.  [1]

 ALC may increase Brain levels of Choline Acetylase.  [2]

 ALC may enhance the function of Cytochrome C Oxidase, also called Complex IV, which is an essential enzyme of the Electron Transport System.  [3]

 ALC may increase the activity of Prostaglandin D2 Synthase.  [4]

Growth Factors

 ALC may increase (free) Insulin-like Growth Factor-1 (IGF-1) levels.  [5]

 ALC may increase the responsiveness of Neurons to Neurotrophic Factors: 

 ALC may retard the decline in Nerve Growth Factor (NGF) that occurs with the progression of the Aging Process.  [6] 

Hormones

 ALC may normalize Beta-Endorphin levels.  [7]

 ALC may prevent the depletion of Luteinizing Hormone Releasing Hormone caused by exposure to excessive Stress.  [8]

 ALC may increase the nighttime secretion of Melatonin by the pineal gland.  [9]

 ALC may increase plasma Testosterone levels (via its influence on Acetylcholine neurotransmission in the Striatal Cortex) and may prevent Testosterone depletion caused by excessive Stress.  [10]

 ALC may increase the body's levels of circulating Thyrotrophin.

Krebs Cycle

 ALC may facilitate the body's production of Acetyl Coenzyme A by donating its Acetyl group to Acetyl Coenzyme A, thereby regenerating Acetyl Coenzyme A from Coenzyme A.  [11]

 ALC may facilitate the production of Adenosine Triphosphate (ATP).  [12] 

Keep reading Acetyl-L-Carnitine

  • Lipids
  • Neurotransmitters
  • Nucleic Compounds
  • Vitamins
  • ALC may Counteract these Potentially Toxic Substances
  • Amino Acids
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