Testosterone

Overview

Testosterone is a steroid hormone primarily produced in the testes in men, the ovaries in women, and the adrenal glands in both sexes. It is a crucial hormone that plays key roles in bodily functions, including reproductive health, muscle mass maintenance, and mood regulation.

 Testosterone - Functions & Health Benefits

 View - Biochemical Pathway

 Testosterone - Factors that Enhance

 Testosterone - Factors that Interfere with

Growth Factors

 Testosterone has a stimulatory effect on the production of Insulin-like Growth Factor-1 (IGF-1).  ^[1]

 Testosterone may stimulate the production of Nerve Growth Factor (NGF) and may increase the number of Nerve Growth Factor Receptors (NGF Receptors).  ^[2]

Hormones

 In males, some Testosterone is converted to Estradiol (catalyzed by Aromatase enzymes):

 50% of male Estradiol production from Testosterone occurs within the Sertoli Cells of the Testicles.

 30% of male Estradiol production from Testosterone occurs within the Muscles.

 Approximately 15% of male Estradiol production from Testosterone occurs within Adipose Tissue.

 Excessive conversion of Testosterone to Estradiol in males is the underlying cause of Gynecomastia (enlarged Breasts in males).

 The conversion of Testosterone to Estradiol in males increases in tandem with the progression of the Aging Process.

Enzymes

 Testosterone may inhibit the activity of Lipoprotein Lipase in Adipocytes (this helps to prevent Obesity).  ^[3]

Hormones

 Testosterone may inhibit excessive Cortisol production.  ^[4]

Immune System Chemicals

 Testosterone may inhibit the production of Interleukin 6 (IL-6).  ^[5]

Proteins

 Testosterone may reduce the production of Amyloid-Beta-Protein Precursor(an endogenous Protein that is involved in the development of Alzheimer’s Disease).  ^[6]

 Testosterone may reduce the production of Amyloid-Beta-Protein Precursor.  ^[7]

 Testosterone may lower elevated Fibrinogen levels.  ^[8]

 Testosterone may lower elevated Lipoprotein (a) levels.  ^[9]

Bee Foods

 Testosterone is claimed to be a constituent of Royal Jelly.  ^[10]

Hair

 Excessive dosages of exogenous, supplementary Testosterone may cause Hirsutism (excessive body Hair growth) in females.

 Excessive Testosterone may indirectly cause Male Pattern Baldness (due to its conversion to Dihydrotestosterone (DHT) by the 5-Alpha Reductase Enzyme).  ^[11]

Hormones

 Testosterone is the immediate precursor for Dihydrotestosterone (DHT):  ^[12]

 Approximately 6% - 10% of the body’s free Testosterone is converted to DHT.

Immune System

 It has been claimed that Testosterone "feeds" Prostate Cancer cells - this subject has been intensely debated by medical experts, some of whom argue that high Testosterone “feeds” Prostate Cancer cells, others believe that Testosterone plays no part in Prostate Cancer progression.  ^[13]

Metabolism

 The Methyltestosterone (exogenous, supplementary and chemically-different to natural Testosterone) form of Testosterone may cause Liver damage.

Nervous System

 Excessive Testosterone production may increase Aggressiveness.  ^[14]

 Testosterone may be implicated in Attention Deficit/Hyperactivity Disorder (ADHD) - ADHD may occur as a result of impeded development of the Corpus Callosum of the Brain - the Corpus Callosum is impeded by excessive Testosterone during its early development.