Schizophrenia
Description
Schizophrenia is a severe Mental Disorder characterized by a disintegration of the process of thinking, loss of contact with reality and loss of emotional responsiveness. Schizophrenia patients usually feel that their thoughts, sensations and actions are controlled by, or shared with others.
Prevalence
Approximately 1.5% of persons in Western nations will be diagnosed with Schizophrenia at some stage of their lives - usually between the ages of 16 and 25.
These Substances may Alleviate Schizophrenia
Amino Acids
Cysteine may alleviate some cases of Schizophrenia (presumably due to its role as a precursor for the endogenous production of Glutathione). [1]
Glycine may reduce the severity of Schizophrenia. [2]
Methionine may alleviate Schizophrenia where Schizophrenia is caused by excess Histamine. [3]
N-Acetyl-Cysteine (NAC) may be useful for the treatment of Schizophrenia. [4]
Sarcosine (2,000 mg per day) may alleviate the symptoms of Schizophrenia. [5]
Enzymes
Many Schizophrenia patients are found to have low levels of Delta-4 Desaturase (the enzyme that converts Clupanodonic Acid to Docosahexaenoic Acid (DHA)). [6]
Low levels of Glutathione Peroxidase may be an underlying cause of Schizophrenia (many Schizophrenia patients exhibit low Glutathione Peroxidase levels). [7]
Growth Factors
Brain-Derived Neurotrophic Factor (BDNF) may help to prevent Schizophrenia. [8]
Hormones
DHEA (Dehydroepiandrosterone) may alleviate Schizophrenia. [9]
Estradiol may alleviate Schizophrenia. [10]
Pregnenolone (30 mg per day) may alleviate Schizophrenia. [11]
Lipids
Omega-3 Fatty Acids may improve the effectiveness of standard Prescribed Medications for the treatment of Schizophrenia: [12]
Many Schizophrenia patients have low levels of Docosahexaenoic Acid (DHA) (due to the lack of Delta-4 Desaturase (the enzyme that catalyzes the conversion of Clupanodonic Acid to DHA) in Schizophrenia patients). [13]
Eicosapentaenoic Acid (EPA) may reduce the symptoms of Schizophrenia. [14]
Schizophrenia patients often have low levels of Prostaglandin E1. [15]
Minerals
Magnesium deficiency has been speculated to be an underlying cause of Schizophrenia. [16]
Manganese may alleviate Schizophrenia. [17]
Selenium deficiency has been speculated to be an underlying cause of Schizophrenia (regions with low levels of Selenium have a higher rate of Schizophrenia compared to regions with adequate Selenium levels in the food chain). [18]
Schizophrenics may excrete excessive amounts of Zinc via their Urine. [19]
Neurotransmitters
Low Histamine levels may cause Schizophrenia. [20]
Peptides
Schizophrenia patients are often found to have low endogenous production of Glutathione. [21]
Prescribed Medications
Galanthamine may be useful for the treatment of Schizophrenia (due to its effects on Nicotinic Receptors in the Brain). [22]
Tranquilizers - Major (i.e. Butyrophenones and Phenothiazines) are often employed in the treatment of Schizophrenia - they achieve their effects by opposing the actions of Dopamine. Drugs from this class commonly used include:
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