Galanthamine

Description

Galanthamine is a acetylcholinesterase, AChE, inhibitor boosting acetycholine, ACh, levels. Galantamine also protects the nicotinic acetylcholine receptor, effectively increasing the activity of acetycholine, ACh. Galanthamine is naturally derived from the bulb of certain species of daffodil, Galanthus nivalis, Snowdrop, Narcissus pseudonarcissus, the common Daffodil or from Lycoris radiata, Red Spider Lily. Galanthamine is synthetically made

Immune System

 Galanthamine may alleviate the residual Paralysis associated with recovery from Poliomyelitis. 

Metabolism

 Galanthamine (16 mg per day) may reduce Pain and Fatigue in Chronic Fatigue Syndrome (CFS) patients (due to its beneficial effects on Acetylcholine function).  ^[1]

Nervous System

 Galanthamine may stimulate Cholinergic Receptors (it functions as a Cholinergic agonist):  ^[2]

 Galanthamine binds to and enhances the function of Nicotinic Receptors in the Brain  It also increases the number of Nicotinic Receptors.  ^[3]

 Galanthamine may improve the condition of (all types of) Dementia patients:  ^[4]

 Galanthamine is utilized in the treatment of Alzheimer's Disease (due to its Acetylcholinesterase inhibiting capabilities):  ^[5]

 Galanthamine may improve the cognitive function of (mild to moderate) Alzheimer’s Disease patients.

 Studies have shown that Galanthamine may improve cognitive performance in 60% of mild to moderately severe Alzheimer’s Disease cases within 9 - 10 weeks and most of these patients continue to show exhibit improvement after two years of continued Galanthamine therapy.

 In addition to inhibiting Acetylcholinesterase, Galanthamine may improve the function of Nicotinic Receptors in Alzheimer’s Disease patients.

 It should be noted that Galanthamine does not permanently halt the cognitive decline that occurs in Alzheimer’s Disease, although it may significantly delay the progression of Alzheimer’s Disease.

 Galanthamine may reduce deposits of Amyloid-Beta-Protein Precursor (APP) and Amyloid-Beta Protein in the Hippocampus.

 Galanthamine may improve the condition of Multiple-Infarct Dementia patients.  ^[6]

 Galanthamine may exert a mild anti-depressant effect and is therefore useful as an adjunct for the treatment of Depression.  ^[7]