Histamine

Description

Histamine is an inhibitory Neurotransmitter.  Chemically, it is a Ptomaine Amine.

Cardiovascular System

 Histamine dilates the Blood Vessels when it is released from Mast Cells.

 Platelets contain small amounts of Histamine which is secreted under certain circumstances.

Cells

 Histamine is a necessary factor for Cells division. 

Digestive System

 Histamine enhances the function of the Digestive System by stimulating the production of Gastric Juice by the Gastric Mucosa. 

Immune System

 Histamine concentrates in Basophils (in the bloodstream) and Mast Cells (in Connective Tissues) of the Immune System - Histamine is released from these Cells as a defense mechanism when Basophils and Mast Cells "burst" in response to antagonism by the Antigens that are responsible for Allergies and during Inflammation:

 Histamine attracts Eosinophils to areas of the body in which Histamine has been deposited.

Nervous System

 Histamine may exert a calming effect as it promotes tranquil Alpha Waves Brain activity.

 Low Histamine levels may cause Anxiety.

 Low Histamine levels may cause Depression:

 Caution:  excess Histamine can also CAUSE Depression.

 Histamine applied topically may alleviate the symptoms of Multiple Sclerosis.  ^[1]

 Low Histamine levels may cause Schizophrenia.  ^[2] 

Sexual System

 Histamine may enhance Sexual Performance as Histamine release from the Mast Cells is a requirement for achieving Orgasm:  ^[3]

 Histamine is responsible for the "hot flush" (blushing in the face, neck, shoulders, and chest) associated with Orgasm.

 Women who are unable to achieve Orgasm are often found to be deficient in Histamine. 

Digestive System Chemicals

 Histamine stimulates the production of Gastric Juice by the Gastric Mucosa:

 Histamine stimulates increased production of Hydrochloric Acid.  ^[4] 

Enzymes

 Histamine inhibits the production and actions of Monoamine Oxidase (MAO) - i.e. it functions as an endogenous MAO Inhibitor.