Histidine

Overview

Histidine is a Basic, Glucogenic Amino Acid.  Researchers are still trying to determine whether Histidine is an essential or non-essential Amino Acid.

Cardiovascular System

 Histidine may alleviate some types of Anemia due to its role as a constituent (comprising 10%) of Hemoglobin.  ^[1]

 Histidine may stimulate the production of Red Blood Cells due to it being a constituent of Hemoglobin. 

 Histidine may lower Blood Pressure in High Blood Pressure patients via its actions on the Autonomic Nervous System. 

Digestive System

 Histidine may improve Digestion by increasing the production of Gastric Juice (via Histamine). 

 Histidine may alleviate Ulcers - Peptic.   

Eyes/Vision

 Histidine deficiency may result in Cataracts. 

 Diets that exclude Histidine result in cataracts within three weeks.  ^[2]

Immune System

 Histidine may be an effective treatment for some Allergies.

 Histidine may regulate the ratio of Helper T-Cells (CD4 Cells) to Suppressor T-Cells (T8 Cells).  ^[3] 

Metabolism

 Histidine may help to prevent the Cross-Linking of the body’s endogenous Proteins.  ^[4]

 Histidine may prevent/reverse Alcohol-induced Liver damage.  ^[5]

Musculoskeletal System

 Fibromyalgia patients often exhibit significantly lower plasma Histidine levels compared to normal subjects.  ^[6]

 Histidine (2,000 - 3,000 mg per day) may alleviate Rheumatoid Arthritis(by stimulating the activity of suppressor T-Cells).  ^[7]

 Histidine may enhance the growth and repair of Tissues.