Coenzyme Q10
Overview
Coenzyme Q10 (CoQ10) is a type of fat-soluble Coenzyme Q (Quinones) - the most important Q Coenzyme for humans. Coq10 helps convert food into energy and is found in almost every cell in the body. Coq10 is a powerful antioxidant similar in molecular structure to Idebenone, Vitamin E and Vitamin K.
Topic Contents
Coenzyme Q10 - Health Benefits
Coenzyme Q10 - Substances Enhanced By
Coenzyme Q10 - Dietary Sources
Coenzyme Q10 - Biochemical Testing of Coenzyme Q10 Status
These Substances Enhance the Function of Coenzyme Q10
Amino Acids
Carnitine enhances the function of Coenzyme Q10. [1]
Methionine activates Coenzyme Q10.
Tyrosine is required for the production of Coenzyme Q10. [2]
Coenzymes
NADH increases the effectiveness of supplemental Coenzyme Q10. [3]
Enzymes
HMG-CoA Reductase is an essential catalyst for the endogenous production of Coenzyme Q10.
Lipids
Cardiolipin facilitates the transportation of Coenzyme Q10 into the Mitochondria of Cells.
Minerals
Selenium enhances the body's production of Coenzyme Q10.
Quinones
Healthy humans can convert Coenzymes Q1- Q9 into Coenzyme Q10 (e.g. 2 x CoQ1 + 4 x CoQ7 = 3 x CoQ10).
Vitamins
Biotin is synergistic with Coenzyme Q10.
Folic Acid is an essential cofactor for the endogenous synthesis of Coenzyme Q10. [4]
Lipoic Acid regenerates Coenzyme Q10. [5]
Vitamin B2 is an essential cofactor for the endogenous synthesis of Coenzyme Q10. [6]
The Niacinamide form of Vitamin B3 is an essential cofactor for the endogenous synthesis of Coenzyme Q10. [7]
Vitamin B5 is synergistic with Coenzyme Q10 and is involved in the endogenous synthesis of Coenzyme Q10. [8]
Vitamin B6 is an essential cofactor for the endogenous synthesis of Coenzyme Q10. [9]
Vitamin B12 is an essential cofactor for the endogenous synthesis of Coenzyme Q10. [10]
Vitamin C is an essential cofactor for the endogenous synthesis of Coenzyme Q10. [11]
Other Factors that Enhance the Function of Coenzyme Q10
Metabolism
Intense Exercise increases the concentration of endogenous CoenzymeQ10 within the Heart and Muscles - i.e. it improves the transport of CoQ10 from the serum to the Heart and Muscles. [12]
Coenzyme Q10 may Reduce the Toxicity of these Substances
Aldehydes
Coenzyme Q10 may lower Malondialdehyde levels. [13]
Amino Acids
Coenzyme Q10 may counteract the toxicity of Glutamic Acid. [14]
Carbohydrates
Coenzyme Q10 may counteract the toxic effects of Lipopolysaccharides (it counteracts Endotoxemia). [15]
Electromagnetic Radiation
Coenzyme Q10 (applied topically) may inhibit the ability of Sunlight to cause premature aging of the Skin. [16]
Enzymes
Coenzyme Q10 may inhibit the activity of arNOX. [17]
Coenzyme Q10 (applied topically) may inhibit the activity of Collagenase in the Fibroblasts of the Dermis of the Skin. [18]
Immune System Chemicals (Cytokines)
Coenzyme Q10 may retard the ability of Tumor Necrosis Factor (TNF) to inhibit the maturation of Oligodendroglia. [19]
Neurotoxins
Coenzyme Q10 may inhibit the ability of many Neurotoxins to destroy Neurons in the Brain: [20]
Coenzyme Q10 may inhibit the ability of to damage Neurons. [21]
Coenzyme Q10 (especially when administered concurrently with NADH) may prevent the depletion of Dopamine caused by the Neurotoxin, MPTP. [22]
Organic Acids
Coenzyme Q10 may protect against the toxic effects of Malonic Acid. [23]
Patented Medicines
Coenzyme Q10 may inhibit the ability of Cisplatin to damage the Kidneys. [24]
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