HMG-CoA Reductase

2 min readEvidence-linked topicGreen Medicine Encyclopedia

Description

HMG-CoA Reductase is a type of Oxidoreductase Enzyme.  Most HMG-CoA Reductase activity occurs in the Liver.

 

HMG-CoA Reductase Enhances the Production of these Substances

Lipids

 HMG-CoA Reductase is an essential catalyst for the endogenous production of the precursor chemicals for Cholesterol:

 Specifically, HMG-CoA Reductase catalyzes the conversion of HMG-CoA to Mevalonic Acid.

 

Quinones

 HMG-CoA Reductase is an essential catalyst for the endogenous production of Coenzyme Q10.

 

These Substances may Inhibit HMG-CoA Reductase

Carbohydrates

 Chitin may inhibit HMG-CoA Reductase. 

 Chitosan may inhibit HMG-CoA Reductase.  [1]

 

Lignans

 Sesaminol may inhibit HMG-CoA Reductase.  [2]

 

Lipids

 Alpha-Linolenic Acid (LNA) may reduce the activity of HMG-CoA Reductase.  [3]

 Docosahexaenoic Acid (DHA) may reduce the activity of HMG-CoA Reductase.  [4]

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