Aging Process - Substances that are Depleted

Description

This section lists the nutrients, hormones and other compounds, naturally present within the human body, whose levels inevitably decline in tandem with the progression of the Aging Process.  It is becoming increasingly common to attempt to restore levels of these compounds to youthful levels, either by directly supplementing with these compounds or by using their precursors in order to counteract their inevitable decline with Aging.

Amino Acids

 Carnitine levels in the Brain, Blood, Heart and Muscles decrease in tandem with the progression of the Aging Process, while Carnitine levels in the Liver increase in tandem with the Aging Process, indicating that the transportation of Carnitine from the Liver to the Blood declines in tandem with the Aging Process:  ^[1]

 The body's (especially the Brain's) levels of Acetyl-L-Carnitine (ALC) decline in tandem with the Aging Process.

 The body’s ability to synthesize Creatine declines in tandem with the progression of the Aging Process:

 Muscle Creatine Phosphate levels decline in tandem with the progression of the Aging Process and the body’s ability to resynthesize Creatine Phosphate after intensive Exercise declines in tandem with the progression of the Aging Process.  ^[2]

 Older cells contain 20% - 30% less Glutathione than young Cells.  ^[3]

 Phenylalanine absorption decreases significantly in tandem with the Aging Process.

 The body’s levels of S-Adenosylmethionine (SAMe) decline in tandem with the progression of the Aging Process.  ^[4]

Carbohydrates

 The content of Chondroitin Sulfate (CSA-B form) in the Dermis of the Skin declines in tandem with the progression of the Aging Process:  ^[5]

 The ratio of Chondroitin Sulfate-A (CSA-A) to Chondroitin Sulfate-C (CSA-C) declines in tandem with the progression of the Aging Process and this form of CSA should therefore be the major supplemental form of CSA.  ^[5]

 The body's production of Hyaluronic Acid declines in tandem with the Aging Process and the body’s excretion of Hyaluronic Acid increases in tandem with the Aging Process:  ^[7]

 The content of Hyaluronic Acid in the Dermis of the Skin declines in tandem with the progression of the Aging Process (the Dermis of people aged 60 and over often contain zero Hyaluronic Acid).

Carotenoids

 The Lutein content of the Eyes declines in tandem with the progression of the Aging Process.  ^[8]

Digestive System Chemicals

 The body's production of Hydrochloric Acid declines in tandem with the Aging Process.  ^[9]

Enzymes

 Cytochrome C Oxidase activity declines in tandem with the progression of the Aging Process.  ^[10]

 The body's production of Delta-6 Desaturase declines in tandem with the Aging Process.  ^[11]

 The body’s production of Digestive Enzymes declines in tandem with the progression of the Aging Process.  ^[12]

 The Skin’s Glutamate Decarboxylase activity and content declines in tandem with the progression of the Aging Process.  ^[13]

 The body’s Glutathione Peroxidase content declines in tandem with the progression of the Aging Process.  ^[14]

 The production and acitivity of Paraoxonase-1 declines in tandem with the progression of the Aging Process.

 The body's production of Superoxide Dismutase (SOD) declines in tandem with the Aging Process.

Growth Factors

 Insulin-like Growth Factor-1 (IGF-1) levels decline in tandem with the progression of the Aging Process.  ^[15]

 Nerve Growth Factor (NGF) production declines in tandem with the Aging Process (the body’s production of NGF peaks at the age of two and then steadily declines thereafter).  ^[16]

Hormones

 The body’s production and levels of Androstenediol declines in tandem with the progression of the Aging Process - 80 year olds have 54% less Androstenediol compared to 35 year olds.  ^[17]