Creatine

Creatine is an Amino Acid that is not a constituent of any Proteins.  It is manufactured in the Liver, Kidneys and Pancreas from Arginine joined to Glycine, attached to a Methyl Group from Methionine. 95% of the body’s Creatine reserves are stored in Skeletal MuscleSkeletal Muscle.

Further health benefits of supplemental Creatine are listed in the topic for Creatine Monohydrate.

Aging & Life Extension

 Creatine may possess Life Extension properties.  ^[1]

Cardiovascular System

 Creatine, Creatine Monohydrate, may be of benefit to Congestive Heart Failure (CHF) patients. CHF patients exhibit endogenous intracellular Creatine levels approximately 20% lower than normal and supplementary Creatine as Creatine Monohydrate, 20 grams per day, may help to restore normal Creatine levels.  ^[2]

 Some of the body’s Creatine pool is stored in the Heart.  ^[3]

Eyes/Vison

 Creatine (including Creatine Monohydrate) (1,500 - 3,000 mg per day) may halt the further progression of Gyrate Atrophy of the Choroid and Retina.  ^[4]

Immune System

 Creatine may counteract the Cachexia associated with Acquired Immune Deficiency Syndrome (AIDS) - Creatine may increase Muscle mass and Muscle Strength in AIDS patients. 

Metabolism

       Creatine possesses Antioxidants properties:          Creatine scavenges Peroxynitrite Free Radicals.  ^[5]

        Creatine scavenges Superoxide Free Radicals.  ^[6]

Musculoskeletal System

 Fibromyalgia patients have significantly lower levels of Creatine than healthy people (and supplemental Creatine Monohydrate may help to restore endogenous Creatine levels to normal in Fibromyalgia patients) - studies to determine whether supplemental Creatine Monohydrate may alleviate Fibromyalgia have not yet been performed.  ^[7]

       Creatine concentrates in the Muscles and supplemental forms of Creatine concentrate in the Muscles  ^[8]

       may improve the condition of Muscle Fibers.  ^[9]

        Muscular Dystrophy patients often excrete excessive amounts of Creatine (a condition known as Creatinuria) in their Urine - this indicates that supplemental Creatine may alleviate Muscular Dystrophy.  ^[10]

 Rheumatoid Arthritis patients often have lower levels of Creatine than healthy people (and supplemental Creatine Monohydrate may help to restore endogenous Creatine levels to normal in Rheumatoid Arthritis patients) - studies to determine whether supplemental Creatine Monohydrate could alleviate Rheumatoid Arthritis have not yet been performed.  ^[11]

Nervous System

 Some of the body’s Creatine pool is stored in the Brain.  ^[12]