Lipofuscin

Also known as:  Age Pigment

Lipofuscin is a type of Lipopigment that occurs within the body as yellow/brown spots which are not freckles, birthmarks or scars.  Lipofuscin fluoresces (glows) a yellow/green/orange/brown color under ultraviolet light.

Amino Acids

 Carnitine may facilitate the removal of Lipofuscin from the Heart:  ^[1]

 Acetyl-L-Carnitine (ALC) may reduce the formation of Lipofuscin in the Brain.  ^[2]

 Creatine may inhibit the accumulation of Lipofuscin in the Brain.  ^[3]

 Magnesium Orotate may prevent the deposition of Lipofuscin in the body's Cells. 

Carotenoids

 Lutein may inhibit the production of Lipofuscin in the Eyes.  ^[4]

 Zeaxanthin may inhibit the production of Lipofuscin in the Eyes.  ^[5]

Enzymes

 Proteasomes may help to prevent the accumulation of Lipofuscin.  ^[6]

Hormones

 It has been hypothesized that Melatonin may facilitate the removal of Lipofuscin from the body.  ^[7]

Minerals

 Chromium deficiency may accelerate the accumulation of Lipofuscin and supplemental Chromium facilitates the removeal of Lipofuscin from the body.  ^[8]

Nucleic Compounds

 Supplemental or dietary Nucleosides may retard the accumulation of Lipofuscin in the Brain.  ^[9]

 Supplemental or dietary Nucleotides may retard the accumulation of Lipofuscin in the Brain.  ^[10]

Polyphenols

 Oligomeric Proanthocyanidins (OPCs) may remove and prevent Lipofuscin formation in the Brain and Heart.  ^[11]

Skin Improvers

 Kinetin (applied topically) may inhibit the accumulation of Lipofuscin in the Skin.  ^[12]

Smart Drugs

 Aminoguanidine may reduce the formation of Lipofuscin.  ^[13]

        Centrophenoxine may reduce (by 25% - 43%) Lipofuscin deposits in all Central Nervous System and Heart tissues.  It may also remove Lipofuscin from the Skin.  ^[14]

        Dimethylaminoethanol (DMAE) may remove all visible Lipofuscin from the Skin.  DMAE may also removes Lipofuscin from Neurons and may decrease the accumulation of Lipofuscin in Heart Muscle.  ^[15]