Aminoguanidine

Description

Aminoguanidine is a synthetic substance regarded as a Smart Drug from the class Advanced Glycation End-product Inhibitors (AGE Inhibitors).  It reduces AGE accumulation, & reduces complications (nerve damage, nephropathy, retinopathy) in diabetic lab rodents.

Health Benefits of Aminoguanidine

Aging & Life Extension

 Aminoguanidine may retard the progression of the Aging Process (it inhibits the Cross-Linking of the body''s endogenous Proteins with Glucose).  ^[1]

 Aminoguanidine may possess Life Extension potential (due to its ability to prevent the Cross-Linking of the body''s endogenous Proteins with Glucose).  

Excretory System

 Aminoguanidine may help to prevent Diabetic Nephropathy in Diabetes Mellitus patients.

 Aminoguanidine may improve the function of the Kidneys (by counteracting Cross-Linking in the Kidneys).  

Eyes/Vision

 Aminoguanidine may help to prevent Cataracts (by inhibiting the Cross-Linking that causes Cataracts).  ^[2]

 Aminoguanidine may be useful for the treatment of (diabetic) Retinopathy.  ^[3]

Immune System

 Aminoguanidine may be useful for the treatment of Cancer - Pancreas.  ^[4]

Metabolism

  Aminoguanidine may inhibit the process of Cross-Linking of the body''s endogenous Proteins with Glucose:  ^[5]

 Aminoguanidine''s ability to inhibit Cross-Linking centers on its ability to form Guanidine-Dicarbonyl adducts, thereby reducing the number of free Carbonyl groups.  It is particularly effective against some types of Aldehydes that contribute to Cross-Linking such as Alpha-Oxaldehyde and Malondialdehyde.