Collagen

7 min readEvidence-linked topicGreen Medicine Encyclopedia

Overview

Collagen is a type of insoluble Fibrous Glycoprotein (i.e., a Scleroprotein) formed within the human body, forming the basis of all Fibrous Connective Tissues within the body.  It is a complex molecule that contains 16,000 atoms.  Collagen comprises 30% of the body's endogenous proteins and is, therefore, the most abundant protein in the body.

Biological Functions of Collagen

Cardiovascular System

 Collagen forms the basis of the Connective Tissues of the walls of Blood Vessels - it provides strength, permeability, and elasticity to the walls of Blood Vessels:

 Collagen is a constituent of the Intima of Blood Vessels.

 Collagen is a constituent of the Media of Blood Vessels.

Excretory System

 Collagen is an essential component of the tiny filters within the Kidneys.

Eyes/Vision

 Collagen is essential to the structural integrity of the Eyes:

 Collagen (Type II Collagen) is a major constituent of the Vitreous Humor of the Eyeball.

Immune System

 Collagen may inhibit the spread of some forms of Cancer.

 Collagen is a constituent of the Intima of Lymph Vessels. 

Musculoskeletal System

 Collagen is an essential component of all Connective Tissue:  [1]

 Collagen is a major component of the Extracellular Matrix
 Collagen is a constituent of the Intima of Lymph Vessels and Blood Vessels.

 Collagen is an essential component of the Intervertebral Discs of the Back.

 Bones contain 40% of the body's total Collagen:

 Collagen is responsible for depositing Calcium Phosphate to form Bone.

 Collagen binds Bone Cartilage and matrix.

 Collagen is essential for the healing of Fractures.

 Collagen (Type II Collagen) is an essential component of Cartilage.

 Collagen is essential to the structural integrity of the Joints.

 Collagen is an essential component of the Muscles.

 Collagen binds Ligaments.

 Collagen binds the fibrous tissues of the Tendons.

 Collagen is a component of the Teeth.

Skin

 Collagen (supplemental Collagen administered orally) may accelerate the healing of Ulcers - Decubitus.  [2]

 Collagen is responsible for the elasticity of the Skin - primarily within the Dermis:  [3]

 Collagen constitutes 70% of the dry weight of the Dermis.  [3]

 The types of Collagen found in the Skin are Collagen - Type I and Collagen - Type III.

 Oral ingestion of exogenous Collagen may increase the density of Fibroblasts in the Dermis, increase the Dermatan Sulfate content of the Dermis, and enhance the formation of Collagen fibrils in the Dermis.

Keep reading Collagen

  • Exogenous Collagen may Enhance the Function of these Substances
  • Carbohydrates
  • Stages of Collagen Production
  • These Substances/Factors may Damage Collagen
  • Electromagnetic Radiation
  • Enzymes
  • 14 more sections
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