Dehydroepiandrosterone Sulfate is a type of Steroid Sexual Hormone Precursor. DHEAS is chemically similar to Dehydroepiandrosterone (DHEA) except for the inclusion of Sulfate in this molecule - DHEAS is predominantly water-soluble, whereas DHEA is predominantly fat-soluble. It is is produced in and secreted by the zona fasciculata and zona reticularis of the Adrenal Gland ...