Osteoporosis - Prevention/Treatment

These Substances may Alleviate/Prevent Osteoporosis

Alkaloids

 Berberine may help to prevent Osteoporosis.  ^[1]

Amino Acids

 Arginine may prevent and treat Osteoporosis (by stimulating the release of Human Growth Hormone which is an important mediator of Bone formation and Bone turnover;  it also stimulates Nitric Oxide production - Nitric Oxide is a potent inhibitor of Bone resorption by Osteoclasts).  ^[2]

 Creatine Monohydrate (5,000 mg per day combined with Isotonic Exercise) may help to prevent Osteoporosis by increasing Bone Mineral content.  ^[3]

 Ethylene-Diamine-Tetra-Acetate (EDTA, the synthetic Amino Acid used in Chelation Therapy) may increase Bone Mineral Density in Osteoporosis patients (it is believed to “work” by “pulsing” Parathyroid Hormone which enhances Calcium metabolism).  ^[4]

 Lysine may help to prevent Osteoporosis (by facilitating the production of Osteoblasts).  ^[5]

Carbohydrates

 Inulin may help to prevent and treat Osteoporosis (by increasing the absorption of Calcium).  ^[6]

 Xylitol may help to maintain Bone density and may thereby help to prevent Osteoporosis (by facilitating the intestinal absorption of Calcium).  ^[7]

Carotenoids

 Cryptoxanthin may help to prevent Osteoporosis (by enhancing the function of Osteoblasts).  ^[8]

 Lycopene may help to prevent Osteoporosis (by stimulating the proliferation of Osteoblasts and by inhibiting the proliferation of Osteoclasts).  ^[9]

Enzymes

 Aromatase may help to prevent Osteoporosis (by catalyzing the conversion of Androstenedione to Estrone in the Bones).  ^[10]

 Superoxide Dismutase (SOD) may help to prevent Osteoporosis by inhibiting the generation of Superoxide Free Radicals that activate Osteoclasts (excessive activation of Osteoclasts is a fundamental cause of Osteoporosis).  ^[11]

Growth Factors

 Insulin-like Growth Factor-1 (IGF-1) may enhance the function of Osteoblasts in Osteoporosis patients.  ^[12]

Hormones

 Androstenedione may help to prevent Osteoporosis in women who have had an :  ^[13]

 Removal of the Ovaries causes a reduction in endogenous Androstenedione production and this may cause subsequent Bone loss.

 Calcitonin may alleviate and prevent Osteoporosis by enhancing the retention of Calcium in the Bones and by inhibiting Osteoclasts.  ^[14]

 Dehydroepiandrosterone Sulfate (DHEA) may protect against Osteoporosis:  ^[15]

 There is a statistically significant correlation between vertebral bone density in postmenopausal women and DHEA levels.

 Estrogens (used in hormone replacement therapy for menopausal women) may reduce the risk of Osteoporosis in menopausal and post-menopausal women (by enhancing the retention of Calcium within the Bones and by inhibiting the ability of Osteoclasts to cause the break down of Bones):  ^[16]

 Estriol may help to prevent Osteoporosis.  ^[17]

 Estrone (produced in Osteoblasts via the Aromatase enzyme) may help to prevent Osteoporosis (by stimulating Osteoblasts).  ^[18]

 Human Growth Hormone (hGH) may build Bone mass and the decline in hGH production that occurs in tandem with the progression of the Aging Process has been implicated by some researchers as a principal underlying cause of Osteoporosis.  ^[19]

 The natural decline in the body's production and secretion of Melatonin that occurs with the progression of the Aging Process may be responsible for post-menopausal cases of Osteoporosis.  ^[20]

 Pregnenolone may be useful for the treatment of Osteoporosis (due to its conversion to Progesterone within the body).  ^[21]

 Supplemental, exogenous, natural Progesterone (especially in post-menopausal females) may prevent and reverse Osteoporosis by stimulating Osteoblast activity:  ^[22]

 Progesterone deficiency may be a major cause of Osteoporosis and clinical studies have shown that supplemental Progesterone may increase bone mass density (BMD) by 7% after 1 year of supplementation, by 12% after two years, and by 15% after three years.  Women administered supplemental Progesterone up to the age of 80 following Menopause often exhibit strong Bones without evidence of Bone loss while continuing to use natural Progesterone.

 Parathyroid Hormone may increase Bone Density in Osteoporosis patients (by improving the body's internal metabolism of Calcium).

 Insufficient endogenous production of Testosterone in males may cause Osteoporosis.  ^[23]

Lipids

 Corosolic Acid may help to prevent/treat Osteoporosis.  ^[24]

 Omega-3 Fatty Acids may reduce the risk of Osteoporosis (by inhibiting the production of pro-inflammatory Eicosanoids such as Prostaglandin E2 and Leukotriene B4 that are known to be involved in the process of Bone resorption):  ^[25]

 Alpha-Linolenic Acid may help to prevent Osteoporosis.  ^[26]