Calcitonin
Also known as: CT; Calcimar; Cibacalcin; Elcatonin; Miacalcin; Thyrocalcitonin
Description
Calcitonin is a Hormone produced in the Thyroid and Parathyroid Glands. Chemically, Calcitonin is a single chain Polypeptide Hormone that is composed of 32 Amino Acids.
The Second Messenger used by Calcitonin is cyclic AMP (cAMP).
Biological Functions and Therapeutic Uses of Calcitonin
Musculoskeletal System
Calcitonin transfers Calcium from the Blood and stores it in the Bones and inhibits the rate of release of Calcium from the Bones (i.e. it inhibits Bone resorption by inhibiting Osteoclasts).
Calcitonin may help to prevent Osteoporosis (due to its ability to retain Calcium in the Bones) and supplemental synthetic Calcitonin may alleviate Osteoporosis. [1]
Calcitonin may inhibit the resorption of Bone in Paget’s Disease patients (by decreasing the activity of Osteoclasts).
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