Panic Disorder

4 min readEvidence-linked topicGreen Medicine Encyclopedia

Overview

Panic Disorder is a severe attack of overwhelming Anxiety (a form of Anxiety).  It is characterized by recurring Panic Attaks.

 

Prevalence

 Approximately 30% of adults in Western nations have experienced at least one Panic Attack in their lifetime.

 

Underlying Mechanisms of Panic Disorder

Nervous System

 Panic Disorder patients have decreased propensity for GABAa Receptors binding.  [1]

 

These Substances may Alleviate Panic Disorder

Amino Acids

 5-HTP (5-Hydroxytryptophan) may alleviate Panic Disorder.  [2]

 Glycine may alleviate the Panic Attacks that occur during Panic Disorder (by antagonizing the stimulatory effects of Norepinephrine in the Brain).  [3]

 Tryptophan may alleviate the symptoms of Panic Disorder.  [4]

 

Enzymes

 Panic Disorder patients generally have lowered Brain activity of Glutamate Decarboxylase.  [5]

 

Growth Factors

 Panic Disorder may occur as a result of reduced Brain-Derived Neurotrophic Factor (BDNF) levels.  [6]

 

Hormones

 It has been speculated that supplemental Pregnenolone may be useful for the treatment of Panic Disorder.  [7]

 

Minerals

 Panic Disorder may occur as a result of Magnesium deficiency.  [8]

 Panic Disorder may occur as a result of Zinc deficiency.  [9]

 

Neurotransmitters

 Panic Disorder patients have been demonstrated to have low Brain levels of Gamma Aminobutyric Acid (GABA), indicating that supplemental GABA (or its precursors) may be useful for the treatment of Panic Disorder.  [10]

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