Spleen

5 min readEvidence-linked topicGreen Medicine Encyclopedia

Description

The Spleen is an organ of the Immune System and Lymphatic System that is located on the left side of the abdomen between the Stomach, Kidneys and Ribs.  It consists almost entirely of Lymphoid Tissue and is the primary organ of the body outside of the Central Nervous System that contains Cannabinoid Receptors.

 

Biological Function of the Spleen

Cardiovascular System

 The Spleen is responsible for the breakdown of spent Hemoglobin.

 

Immune System

 The Spleen is responsible for the production of some types of Antibodies in response to Antigens.

 The Spleen facilitates the interaction of B-Lymphocytes, T-Lymphocytes, Macrophages and Antibodies.

 B-Lymphocytes are converted to Plasma Cells in response to Antigens within the white pulp of the Spleen.

 Spleen Peptides are produced by the Spleen:

 Splenopentin (a Pentapeptide) is produced by the Spleen. Tuftsin (a Tetrapeptide) is produced by the Spleen.

 The Spleen facilitates the recirculation of White Blood Cells.

 

Metabolism

 Pyrimidines are manufactured by the body within the Spleen.

 

These Substances may Enhance the Function of the Spleen

Poor Spleen function is known medically as Hyposplenia.

 

Alkaloids

 Berberine may improve the function of the Spleen by improving Blood Circulation to the Spleen.  [1]

 Swainsonine may stimulate cells within the Spleen to exert antimetastatic effects against various forms of Cancer. 

 

Amino Acids

 Aspartic Acid (Magnesium Aspartate combined with Potassium Aspartate) may stimulate the proliferation and differentiation of Spleen tissue.  [2]

 

Carotenoids

 Beta-Carotene concentrates in the Spleen.

 Lycopene concentrates in the Spleen.

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