Cancer - Skin
Description
Skin Cancer is a group of Cancers that involve malignant tumor(s) in the Skin.
Prevalence
Overall, Skin Cancer is the sixth most common type of Cancer to affect men and the seventh most common type of Cancer to affect women.
Approximately 50% of persons in Western nations who reach the age of 65 will develop some form of Skin Cancer at some stage.
These Substances may Help to Prevent Skin Cancer
Alkaloids
Sanguinarine (applied topically) may help to prevent Skin Cancer. [1]
Auxins
Indole-3-Carbinol may help to prevent Skin Cancer (especially Papilloma Virus-initiated Skin Cancer). [2]
Amino Acids
Cysteine (especially the N-Acetyl-Cysteine (NAC) form of Cysteine) may help to prevent Skin Cancer. [3]
Antioxidants (synthetic)
Butylated Hydroxytoluene (BHT) may help to prevent Ultra-Violet Radiation-induced Skin Cancer. [4]
Carbohydrates
D-Glucaric Acid may help to prevent Skin Cancer. [5]
Carotenoids
Alpha-Carotene (administered orally or applied topically) may help to prevent Skin Cancer: [6]
Alpha-Carotene is claimed to be ten times more effective at preventing Skin Cancer than Beta-Carotene.
Beta-Carotene may help to prevent (both chemically-induced and Ultra-Violet Radiation-induced) Skin Cancer (especially the Squamous Cell Carcinoma form). It should be noted that Alpha-Carotene may be more effective for the prevention of Skin Cancer than Beta-Carotene. [7]
Canthaxanthin may help to prevent (Ultra-Violet Radiation-induced) Skin Cancer. [8]
Capsanthin may help to prevent Skin Cancer. [9]
Crocetin (applied topically) may reduce the ability of some carcinogens to cause Skin Cancer. [10]
Fucoxanthin may help to prevent Skin Cancer.
Lutein may help to prevent Sunlight-induced Skin Cancer. [11]
Cosmeceuticals
Glycolic Acid (applied topically) may help to prevent (Ultra-Violet Radiation-induced) Skin Cancer. [12]
Retin-A may prevent some types of Skin Cancer:
Retin-A changes precancerous cells in the Epidermis of the Skin back to normal cells.
Sunscreens (applied topically) help to prevent some types of Skin Cancer (but not the Melanoma form of Skin Cancer): [13]
One of the underlying mechanisms through which Sunscreens prevent Skin Cancers other than Melanoma is by protecting the p53 Tumor Suppressor Gene in the Skin from the damage inflicted by excessive exposure to the Ultra-Violet Radiation component of Sunlight. [14]
Enzyme Inhibitors
Protease Inhibitors may inhibit the development of Skin Cancer.
Enzymes
Bromelain may help to prevent Skin Cancer. [15]
Hormones
DHEA (Dehydroepiandrosterone) (consumed orally or applied topically) may help to protect against Skin Cancer. [16]
Lipids
Eicosapentaenoic Acid (EPA) may help to prevent Skin Cancer. [17]
Limonene may help to prevent Skin Cancer. [18]
Resveratrol may help to prevent Skin Cancer. [19]
Some carcinogenic chemicals may be inactivated by the Squalene component of Sebum (implying that topically-applied Squalene may prevent Skin Cancer via this inactivation of Skin carcinogens). [20]
Minerals
Selenium may prevent several forms of Skin Cancer by stimulating the anti-carcinogenic actions of Phagocytes. [21]
Sodium Bicarbonate may be a viable therapy for Skin Cancer.
Organic Acids
Inositol Hexaphosphate (applied topically) may help to prevent Skin Cancer. [22]
Polyphenols
Apigenin (applied topically along with a suitable carrier vehicle that permits topical Apigenin to permeate through to the Epidermis (e.g. Dimethyl Sulfoxide (DMSO)) may help to prevent Skin Cancer. [23]
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