Cancer - Cervix

Overview

Cervical Cancer involves the growth/development of malignant tumor(s) in the Cervix. 

Prevalence

 Cervical Cancer is the ninth most common cause of death in women in the USA and is the second most common form of Cancer that afflicts women in the developing world.  It accounts for 11.6% of all human Cancers worldwide.

 According to the American Cancer Society, 12,900 new cases of cervical cancer will be diagnosed and 4,100 women will die from the disease in 2015.

 Cervical Cancer occurs most commonly in women aged 50+. 

Alkaloids

 Berberine may inhibit the growth of Cervical Cancer cells.  ^[1]

Auxins

 Ascorbigen may help to prevent Cervical Cancer (by indirectly reducing levels of 16-Hydroxyestrone). 

 Diindolylmethane (DIM) may inhibit the development of Cervical Cancer (by inhibiting the conversion of Estrone to its carcinogenic metabolite - 16-Hydroxyestrone; and redirecting Estrone to be converted to its safe metabolite - 2-Hydroxyestrone).  ^[2]

 Indole-3-Carbinol may help to prevent Cervical Cancer (especially Papilloma Virus-initiated Cervical Cancer):  ^[3]

 The principal underlying mechanism for the ability of Indole-3-Carbinol to prevent Cervical Cancer involves the ability of Indole-3-Carbinol to inhibit the ability of Papilloma Virus 16 to stimulate the conversion of Estrone to 16-Hydroxyestrone (a byproduct of Estrone that is a known initiator of Cervical Cancer).

Carbohydrates

 PSP (a constituent of Karawatake Mushrooms) may improve the condition of Cervical Cancer patients.  ^[4]

Carotenoids

 Alpha-Carotene may help to prevent Cervical Cancer.  ^[5]

 Beta-Carotene may protect the body against Cervical Cancer.  ^[6]

 Cryptoxanthin may help to prevent Cervical Cancer.  ^[7]

 Lycopene may protect the body against Cervical Cancer (in one study, women with high serum Lycopene levels have an 80% reduced risk of developing Cervical Cancer compared to women with low serum Lycopene levels).  ^[8] 

Hormones

 Increased production of 2-Hydroxyestrone is associated with a reduction in the risk of Cervical Cancer (Cervix Cancer) - this occurs because 2-Hydroxyestrone production from Estrone is an indicator of reduced conversion of Estrone to 16-Hydroxyestrone (the metabolite of Estrone that is implicated in Cervical Cancer).  ^[9]

Lipids

 Betulinic Acid may stimulate the apoptosis (cell death) of Cervical Cancer cells.  ^[10]

Minerals

 Germanium may be useful for the treatment of Cervical Cancer.  ^[11]

 Selenium may reduce the risk of Cervical Cancer:  ^[12]

 Geographical areas of the world with the highest dietary Selenium intake are associated with lower rates of Cervical Cancer.