Phosphatidylcholine

Also known as:  ABVA-1;  Lecithin (incorrect name although Lecithin does contain Phosphatidylcholine);  Lipostabil;  PC;  Phosphatidyl Choline

Phosphatidylcholine is a type of Phosphoglyceride Phospholipid.

Phosphatidylcholine is a combination of these substances:

Aging & Life Extension

 The body's endogenous Phosphatidylcholine levels decline in tandem with the Aging Process and Phosphatidylcholine (especially when administered via intravenous infusion) may reverse the deterioration of Cell Membranes that ocurs in tandem with the progression of the Aging Process.  ^[1]

 Phosphatidylcholine may possess Life Extension potential: 

-           As the body's Cell Membranes age, they contain less Phosphatidylcholine, and more Cholesterol causing them to become less fluid and more rigid.

-           Old rats incorporate more Phosphatidylcholine into their Cell Membranes than do young rats, indicating that Phosphatidylcholine may reverse this degenerative condition that is associated with the Aging Process.

Cardiovascular System

 Phosphatidylcholine (especially when administered via intravenous infusion) may improve the condition of Angina patients.  ^[2]

 Phosphatidylcholine (especially when administered via intravenous infusion) helps to prevent and treat Atherosclerosis.  ^[3]

 Phosphatidylcholine helps to maintain the elasticity of Blood Vessels.

Cells

 Phosphatidylcholine is essential for the formation of Cell Membranes and is essential for the structural and functional integrity of Cell Membranes.  Supplemental Phosphatidylcholine enhances the function of Cell Membranes throughout the body and comprises approximately 65% of most Cell Membranes.  ^[4]

Digestive System

 Phosphatidylcholine may help to prevent Colitis.  ^[5]

 Phosphatidylcholine is essential for the initial emulsification of dietary Fats (as a constituent of Bile) prior to their further digestion:

 Phosphatidylcholine may prevent and dissolve Gallstones and Kidney Stones by emulsifying their constituent Lipids.  ^[6]

 (Synthetic) Medium-Chain Triglycerides (MCTs) require less Phosphatidylcholine for their emulsification than natural Triglycerides (due to their relatively short Fatty Acid chains that cause them to be more water-soluble than naturally occurring Triglycerides).

 Phosphatidylcholine inhibits the ability of Alcohol (ethanol) and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) to cause Ulcers - Gastric.  ^[7]

 Phosphatidylcholine may reduce Intestinal Permeability (it has been demonstrated to reduce bacterial translocation).  ^[8]

 Phosphatidylcholine inhibits the ability of Alcohol (ethanol) to damage the Pancreas:  ^[9]

 Phosphatidylcholine inhibits the ability of Alcohol (ethanol) to cause Pancreatitis.  ^[10]

 Phosphatidylcholine (especially delayed release form of Phosphatidylcholine – 6,000 mg per day) may alleviate Ulcerative Colitis.  ^[11]

Ears/Hearing

 Phosphatidylcholine may help to prevent Hearing Loss - Age-Related.  ^[12]

Metabolism

 Phosphatidylcholine is essential for the correct metabolism of Cholesterol:  ^[13]

 Phosphatidylcholine helps to keep Cholesterol soluble.

 Phosphatidylcholine may inhibit the absorption of dietary Cholesterol.

 Phosphatidylcholine keeps Cholesterol isolated from the lining of Arteries.

 Phosphatidylcholine may prevent the oxidation of Low Density Lipoproteins.  ^[14]

 Phosphatidylcholine is an essential component of High Density Lipoproteins (HDL) - it comprises 22% of HDL.  ^[15]

 Phosphatidylcholine is an essential component of  Low Density Lipoproteins(LDL).

 Supplemental Phosphatidylcholine (12,000 mg per day) may increase High Density Lipoproteins levels (by up to 16%).  ^[16]

 Phosphatidylcholine may help to prevent and treat Cirrhosis (including alcholic Cirrhosis).  ^[17]

 Phosphatidylcholine may help to prevent and treat Fatty Liver.  ^[18]

 Phosphatidylcholine is essential for the detoxification functions of the Liver.  ^[19]

 The Polyunsaturated Fatty Acid form of Phosphatidylcholine (1,800 mg per day) may be beneficial for the treatment of most forms of Hepatitis including: