DHEA - Substances Enhanced by

Introduction

This section lists body chemicals and other substances whose function is enhanced in the presence of optimal or supplemental DHEA.

Growth Factors

 Supplemental DHEA (50 mg per day) may increase Insulin-like Growth Factor-1 (IGF-1) levels (probably by decreasing the binding of IGF-1 to Insulin-like Growth Factor Binding Protein-1, thereby increasing the bioavailability of IGF-1 to tissues).  ^[1]

Hormones

 Some endogenous DHEA may be transformed into its derivative, 7-Keto DHEA.  ^[2]

 Supplemental DHEA (50 mg per day) may increase Androgens production:  ^[3]

 DHEA is the immediate metabolic precursor for endogenous Androstenedione (which in turn is the immediate precursor for Testosterone).  Supplemental DHEA may increase serum Androstenedione levels.  ^[4]

 DHEA (50 mg per day) may increase serum levels of Testosterone in men to levels equal to those of younger men and also slightly increases Testosterone levels in women.  ^[5]

            DHEA may enhance the ability of Albumin to transport Testosterone to various tissues within the body.  ^[6]

 DHEA helps to maintain Cortisol balance (), preventing elevated Cortisol levels.  ^[7]