Helper T-Cells - TH2

4 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  TH2 Helper Cells;  TH2 Helper T-Cells;  T-Helper-2 Cells

 

Description

TH2 Helper T-Cells are one of the two types of Helper T-Cells.

 

Ideally, TH2 Helper T-Cells should be in equal balance with TH1 Helper T-Cells.  When either subset of Helper T-Cells dominate, illness results.

 

Biological Function of TH2 Helper Cells

Cytokines

 TH2 Helper T-Cells release Interleukin 3 (IL-3).

 TH2 Helper T-Cells release Interleukin 4 (IL-4) which is subsequently involved in the differentiation of B-Lymphocytes.

 TH2 Helper T-Cells release Interleukin 5 (IL-3).

 TH2 Helper T-Cells release Interleukin 6 (IL-6) which is subsequently involved in the differentiation of B-Lymphocytes.

 TH2 Helper T-Cells release Interleukin 9 (IL-9).

 TH2 Helper T-Cells release Interleukin 10 (IL-10) which is subsequently involved in the differentiation of B-Lymphocytes.

 TH2 Helper T-Cells release Interleukin 13 (IL-13).

 

Immune System

 TH2 Helper T-Cells are primarily responsible for the Humoral Immunity arm of the Immune System which involves the differentiation of B-Lymphocytes which leads to Antibodies responding to and limiting the damage induced by extracellular Detrimental Microorganisms.

 

These Substances may Inhibit Excessive TH2 Helper T-Cells Activity

Cytokines

 Interleukin 12 may prevent the activation of TH2 Helper T-Cells.  [1]

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