Folic Acid - Substances Enhanced By

4 min readEvidence-linked topicGreen Medicine Encyclopedia

Introduction

This section lists other nutrients and substances whose absorption of function is enhanced in the presence of Folic Acid.

 

Folic Acid may Enhance the Function of these Substances

Alkaloids

 Folic Acid supplementation may increase Betaine levels.  [1]

 

Amino Acids

 Folic Acid is essential for the production of Serine from Glycine. 

 Folic Acid is essential for the methylation of Histidine.  [2]

 Folic Acid facilitates the endogenous production of S-Adenosylmethionine (SAMe).  [3]

 Folic Acid facilitates the convesion of Phenylalanine to Tyrosine (it is a cofactor for Phenylalanine Hydroxylase, the Enzyme that catalyzes the conversion of Phenylalanine to Tyrosine).  [4]

 Folic Acid is essential for the production of Serine from Glycine.  [5]

 Folic Acid is a cofactor for the conversion of Tryptophan to other endogenous substances.

 Folic Acid is an essential cofactor for the conversion of Tyrosine to L-Dopa.

 

Enzymes

 Tetrahydrobiopterin (which is dependent upon Folic Acid) is an essential cofactor for Nitric Oxide Synthase.  [6]

 Folic Acid is an essential cofactor for Phenylalanine Hydroxylase.  [7]

 

Hormones

 Folic Acid is involved in the production of Melatonin (Folic Acid is required for the production of S-Adenosylmethionine (SAMe), the cofactor for the Hydroxyindole-O-Methyltransferase (HIOMT) enzyme that catalyzes the conversion of N-Acetyl-Serotonin to Melatonin).  Folic Acid deficiency has been demonstrated to lead to decreased production of Melatonin in the Pineal Gland.  [8]

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