Spironolactone

Brand Names:  Aldatone;  Aldactone;  Aldoctone;  Spiroctan

Spironolactone is a type of Antiandrogen Pharmaceutical Drug - it is a synthetic Steroid.  Spironolactone is also classed as a type of Potassium-Sparing Pharmaceutical Diuretic.

Cardiovascular System

 Spironolactone may lower elevated Blood Pressure in High Blood Pressure patients (in its role as a Potassium-Sparing Diuretic it increases the volume of Urine, thereby lowering Blood Pressure.

Hair

 Spironolactone (50 - 200 mg per day) is commonly prescribed for the treatment of Hirsutism in women (it achieves its effects by minimizing the effects of Androgens).  ^[1]

Skin

 Spironolactone (150 - 200 mg per day) is sometimes utilized for the treatment of Acne (due to its ability to reduce the production of Sebum by the Sebaceous Glands).

Although Spironolactone is said to "interfere" with the following endogenous substances, it was developed specifically to minimize certain physiological effects of these enzymes/hormones.