Prostaglandin I2

2 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  Epoprostenol;  Prostacyclin;  Prostacyclin I2;  PGI2

 

Description

Prostaglandin I2 is a type of Series 2 Prostaglandin - it is synthesized in the walls of Blood Vessels.

 

 View the Metabolic Pathway for Prostaglandin I2

 

Biological Function of Prostaglandin I2

Cardiovascular System

 PGI2 inhibits abnormal Blood Clotting (it potently inhibits Platelet Aggregation).  [1]

 PGI2 causes of Blood Vessels.

 PGI2 helps to prevent Heart Attack (by inhibiting abnormal Blood Clotting and by causing the vasodilation of Blood Vessels).

 

Immune System

 PGI2 has been studied in the test tube and found to be a potent inhibitor of (and exogenous PGI2 or stimulation of the endogenous production of PGI2 is therefore of potential value for the treatment of various forms of Cancer) - conversely, inhibition of PGI2 production causes an increase in the metastasis of Cancer Cells.  [2]

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