Proteoglycans
Description
Proteoglycans are Glycosaminoglycans that are bound to Proteins.
Proteoglycans are also Glycoproteins but consist of much more Carbohydrate than Protein; that is, they are huge clusters of carbohydrate chains often attached to a Protein backbone.
Biological Function of Proteoglycans
Cardiovascular System
Proteoglycans are a major constituent of the Intima layer of Blood Vessels (where they help to provide structural support).
Immune System
Proteoglycans are a major constituent of the Intima layer of Lymph Vessels (where they help to provide structural support).
Musculoskeletal System
Proteoglycans are a major constituent of the Extracellular Matrix of Connective Tissue: [1]
Proteoglycans are a major constituent of Cartilage.
Proteoglycans are a constituent of the Intima of Blood Vessels and Lymph Vessels.
Skin
Proteoglycans are present in the Extracellular Matrix of the Skin where they facilitate the retention of Water in the Skin (and thereby help to prevent Skin - Dry).
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- These Substances may Enhance the Function of Proteoglycans
- Amines
- Carbohydrates
- Minerals
- Peptides
- These Factors may Damage Proteoglycans
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