IgG

3 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  Gamma Globulin;  Immunoglobulin G

 

Description

IgG is a type of Antibody (Immunoglobulin) that is further sub-classified into IgG1, IgG2, IgG3 and IgG4.

 

IgG comprises 75% of the total Antibody content of Blood Plasma in normal adults.

 

Biological Function of IgG

Immune System

 IgG bind to many typs of Microorganisms - Detrimental and provides protection against these Detrimental Microorganisms vis several mechanisms including:

 Agglutination and immobilization

 Compliment activation

 Opsonization for phagocytosis

 Neutralization of toxins produced by Detrimental Microorganisms

 Antibody-dependent cell-mediated cytotoxicity(ADCC)

 IgG permeates the body's tissues during Inflammation and stimulates Phagocytes to engulf Antigens.

 

Respiratory System

 IgG helps to prevent recurrent Respiratory Tract Infections (patients with sub-optimal IgG levels generally experience recurrent Respiratory Tract Infections):  [1]

 Sub-optimal IgG levels may increase the severity of Influenza.

Keep reading IgG

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