Catechol-O-Methyltransferase

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  COMT

 

Description

Catechol-O-Methyltransferase is a type of (endogenous) Transmethylase Transferase Enzyme.  It is present in most body tissues.

 

Biological Function of COMT

Nervous System

 COMT catalyzes the metabolism of various Catecholamines to their metabolic products for excretion via the Urine:

 Caution:  excessive metabolism of Catecholamines by COMT can cause the depletion of Catecholamines.

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