Tissue Plasminogen Activator

2 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  Activase;  t-PA;  Tissue-Type Plasminogen Activator;  TPA

 

Description

Tissue Plasminogen Activator is a type of Serine Protease Hydrolase Enzyme.

 

Biological Function of Tissue Plasminogen Activator

Cardiovascular System

 Tissue Plasminogen Activator helps to prevent abnormal Blood Clotting (by catalyzing the activation of Plasminogen to Plasmin).

 Optimal Tissue Plasminogen Activator levels prevent the occurrence of Varicose Veins.

 

Therapeutic Usage of Exogenous Tissue Plasminogen Activator

Cardiovascular System

 Tissue Plasminogen Activator may be a beneficial treatment for (ischemic) Stroke when administered within three hours of the occurrence of an ischemic Stroke - it totally dissolves the abnormal Blood Clots that cause ischemic Strokes.  [1]

 

Tissue Plasminogen Activator Enhances the Function of these Substances

Enzymes

 TPA catalyzes the enzymatic conversion (activation) of Plasminogen to Plasmin.

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