Chloasma
Also known as: Melasma; Mask-of-Pregnancy
Description
Chloasma is a patchy, brown discoloration of the Skin - usually on the forehead, temples and cheeks.
Causes of Chloasma
Hormones
Chloasma occurs as a result of excessive and uneven production of Melanin in the Skin:
This uneven distribution of Melanin may occur as a result of excessive activity of the Tyrosinase enzyme in the afflicted areas of the Skin (Tyrosinase catalyzes the conversion of Tyrosine to Melanin).
These Substances may Alleviate Chloasma
Carotenoids
Beta-Carotene (applied topically) may alleviate Chloasma. [1]
Cosmeceuticals
Retin-A (applied topically) may alleviate Chloasma. [2]
Skin-Bleaching Creams (applied topically) which usually contain Hydroquinone as their active ingredients are the most frequent means of alleviating Chloasma.
Lipids
Ceramide 3A (applied topically) may inhibit the synthesis of Melanin in the Skin, making it useful for the treatment of Chloasma.
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