Angiotensin Converting Enzyme

Also known as:  ACE;  Angiotensin-I-Converting Enzyme;  Kininase II;  Peptidyl-Dipeptidase A

 

Angiotensin Converting Enzyme is a type of Enzyme that is located on the inner lining (endothelium) of the Blood Vessels and the Lungs.

 

Cardiovascular System

 ACE catalyzes the activation of Angiotensin 1 (inactive form of Angiotensin) to its active form (Angiotensin 2)- thereby facilitating the constriction of Blood Vessels and resulting in increased Blood Pressure.

 

 

Amino Acids

 Arginine (especially when administered intravenously but possibly also when consumed orally) may inhibit ACE.  ^[1]

 

Microorganisms

 Bifidobacteria longum may inhibit ACE.  ^[2]

 

Peptides

 C12 Peptide may inhibit the ACE.  ^[3]

 

Prescribed Medications

 ACE Inhibitors inhibit ACE, thereby preventing ACE from catalyzing the activation of Angiotensin to its active Angiotensin 2 form (usually in order to lower Blood Pressure in Hypertension patients).