Non-Steroidal Anti-Inflammatory Drugs

Description

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are a large group of Prescribed Medications that inhibit Inflammation by inhibiting the endogenous enzymes that catalyze the production of Prostaglandins.

 The newer NSAIDs are generally no more effective in the treatment of Inflammation than Salicylates (Aspirin).  Their sole advantage over Salicylates is that they produce less gastric irritation).

 Newer NSAIDs cost between $60 and $200 per month (compared to Aspirin which costs approximately $10 per month).

Immune System

 NSAIDs (long-term use) may help to prevent Cancer - Breast (due to their ability to inhibit the Cyclooxygenase-2 (COX-2) enzyme that is involved in Breast Cancer).  ^[1]

 NSAIDs (when used for extended periods) may reduce the risk of Cancer - Colon (due to their ability to inhibit the Cyclooxygenase-2 (COX-2) enzyme that is involved in Colon Cancer).  ^[2]

 NSAIDs may help to prevent Cancer - Prostate.  ^[3]

 NSAIDs suppress Inflammation (by inhibiting the Cyclooxygenase enzyme that is involved in the inflammatory process).

Musculoskeletal System

 NSAIDs are commonly prescribed to alleviate the Inflammation associated with Inflammatory Joint Diseases.

 NSAIDs are commonly employed in the treatment of Osteoarthritis:

 Caution:  although NSAIDs suppress the Pain associated with Osteoarthritis, their prolonged use is associated with an acceleration of the progression of Osteoarthritis and increased Joint destruction.  ^[4]