Phosphodiesterase-5 Inhibitors

Also known as:  PDE-5 inhibitors;  PDE5 Inhibitors

Phosphodiesterase-5 Inhibitors are a group of Anti-Impotence Prescribed Medications.

Sexual System

 Phosphodiesterase-5 Inhibitors are used for the treatment of Impotence - Male (they facilitate erections in Male Impotence patients).

 Phosphodiesterase-5 Inhibitors inhibit Phosphodiesterase-5 (PDE5, an endogenous enzyme that permits Blood to flow out of the Penis), thereby helping to sustain erections: 

 By inhibiting the Phosphodiesterase-5 enzyme in the Penis, Phosphodiesterase-5 Inhibitors permit cyclic GMP to remain active and this is the underlying means by which Phosphodiesterase-5 Inhibitors maintain erections.

 Phosphodiesterase-5 Inhibitors only “work” for Male Impotence as an adjunct to Sexual Arousal (i.e. they do not cause erections in the absence of Sexual Desire).

 Tadalafil (Cialis)

       Udenafil (Zydena)

 Vardenafil (Levitra)

 Sildenafil (Viagra)