Phosphodiesterase-5
Also known as: PDE-5
Description
Phosphodiesterase-5 is a type of Phosphodiesterase enzyme. It is present in the Penis.
Biological Function of Phosphodiesterase-5
PDE-5 catalyzes the hydrolysis (breakdown) of Cyclic GMP to form Guanosine Monophosphate (GMP). [1]
These Substances Inhibit Phosphodiesterase-5 Activity
Alkaloids
Berberine may inhibit Phosphodiesterase-5. [2]
Prescribed Medications
Viagra (selectively and temporarily) inhibits Phosphodiesterase-5 activity (and this is the underlying means by which Viagra causes its effects on male Sexual Performance). [3]
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