Tadalafil

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  Cialis

 

Description

Tadalafil is a type of Phosphodiesterase-5 Inhibitor Pharmaceutical Drug.

 

Therapeutic Usage of Tadalafil

Sexual System

 Tadalafil alleviates Impotence - Male (by blocking Phosphodiesterase-5 (PDE5, an endogenous enzyme that permits Blood to flow out of the Penis, thereby helping to sustain erections).  [1]

 

Tadalafil Enhances the Function of these Substances

Second Messengers

 Tadalafil enhances the activity of Cyclic GMP.  Tadalafil inhibits the Phosphodiesterase 5 (PDE5) enzyme that in turn inhibits cyclic GMP activity.  By inhibiting PDE5 activity, cyclic GMP is able to persist in its activity.

 

Pharmaceutical Availability of Tadalafil

Oral Products

 Tadalafil is available from pharmacies (prescription required) in the form of:

 10 mg tablets (Cialis)

 20 mg tablets (Cialis)

 

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