Leukotriene B4
Also known as: LTB4
Description
Leukotriene B4 is a type of Series 4 Leukotriene.
Biological Function of Leukotriene B4
Immune System
Leukotriene B4 functions as a highly potent chemoattractant for Neutrophils - it stimulates adherence, degranulation and Free Radical formation by Neutrophils. [1]
These Substances may Enhance the Production of Leukotriene B4
Lipids
Arachidonic Acid is the precursor for the production of Leukotriene B4 (via several intermediate compounds): [2]
- View the Metabolic Pathway for Leukotriene B4 Production
Toxic Effects of Leukotriene B4
Cardiovascular System
Excessive production/activity of Leukotriene B4 may be implicated in Atherosclerosis. [3]
Digestive System
Excessive production and activity of Leukotriene B4 may be implicated in Celiac Disease. [4]
Excessive production of Leukotriene B4 may be implicated in the Inflammation that occurs in Crohn’s Disease patients. [5]
Excessive production of Leukotriene B4 may be implicated in the Inflammation (of the Bowel) that occurs in Ulcerative Colitis patients. [6]
Immune System
Leukotriene B4 is involved in (and excessive production causes) Inflammation. [7]
Metabolism
Excessive production of Leukotriene B4 may stimulate the Inflammation that occurs in Pancreatitis patients.
Musculoskeletal System
Excessive production of Leukotriene B4 may be implicated in the Inflammation associated with Rheumatoid Arthritis. [8]
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- Respiratory System
- Sexual System
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- These Substances may Suppress Leukotriene B 4
- Alkaloids
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