Dihomo-Gamma Linolenic Acid

3 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  DGLA;  DHLA;  DHGLA

 

Description

Dihomo-Gamma Linolenic Acid is a type of endogenous Polyunsaturated Fatty Acid (20:3w6) (20:3n6).

 

DGLA normally comprises less than 1.19% of total fasting Red Blood Cell Fatty Acids.

 

Health Benefits of DGLA

Lipids

 DGLA is a precursor for the endogenous production of further Polyunsaturated Fatty Acids, Series 1 Prostaglandins, Series 1 Thromboxanes and Series 3 Leukotrienes:

            View Dihomo-Gamma-Linolenic Acid's Metabolic Pathway

 Delta-5 Desaturase converts DGLA to Arachidonic Acid only when its preferred route (of converting the Omega-3 Fatty Acid Eicosatetraenoic Acid to Eicosapentaenoic Acid) is blocked.

 DGLA CAN convert to the beneficial Series 1 Prostaglandins (e.g. Prostaglandin E1) in the absence of Delta-5-Desaturase.  [1]

 

DGLA may Inhibit these Potentially Toxic Substances

Immune System Chemicals

 DGLA may reduce Tumor Necrosis Factor-alpha (TNF-a) levels.  [2]

Keep reading Dihomo-Gamma Linolenic Acid

  • Lipids
  • These Substances may Enhance the Production/Function of DGLA
  • Enzymes
  • Vitamins
  • These Foods may Enhance the Production of DGLA
  • Oils (dietary Oils)
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