Glucose-6-Phosphate

Description

Glucose-6-Phosphate is an ester of Glucose with Phosphoric Acid.

Metabolism

 Glucose-6-Phosphate is the first metabolic product produced from Glucose during the process of (it is a constituent of resting Muscles):

 View Glucose-6-Phosphate's Role in the Process of Glycolysis

Enzymes

 Glucokinase catalyzes the conversion of Glucose (together with Adenosine Triphosphate (ATP) to Glucose-6-Phosphate (and Adenosine Diphosphate (ADP).

 Glucose-6-Phosphatase catalyzes the dephosphorylation of Glucose-6-Phosphate to free Glucose (which subsequently enters the bloodstream and increases Blood Sugar levels).

 Glucose-6-Phosphate Dehydrogenase (G6PD) catalyzes the oxidation of Glucose-6-Phosphate:

 In the presence of the coenzyme Nicotinamide Adenine Dinucleotide Phosphate (NADP), G6PD oxidizes Glucose-6-Phosphate to 6-Phosphogluconolactone and Nicotinamide Adenine Dinucleotide Phosphate Hydrogen (NADPH).