Guanine

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  G;  Gua

 

Description

Guanine is a type of Purine (one of the two major Purines that occurs in all Nucleic Acids).

 

Biological Function of Guanine

Nucleic Acids - Polynucleotides

 Guanine is an essential component of Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA):

 Guanine forms part of the Nucleotide portion of the DNA unit.

 

Nucleic Acids - Bases

 Guanine is a component of Guanosine.

 

These Substances Enhance the Function of Guanine

Enzymes

 The Guanine Deaminase enzyme catalyzes the conversion of Guanine into Xanthine and Ammonia in the Liver (i.e. it catalyzes the first step in the endogenous degradation of Guanine).

 

Dietary Sources of Guanine

Herbs

 Guanine is a constituent of Hawthorn.

 

Yeasts

 Guanine is a constituent of Brewer's Yeast (which contains approximately 254 mg of Thymine per 100 grams).

 

These Factors Interfere with Guanine

Free Radicals

 Hydroxyl Free Radicals (if generated near endogenous DNA) may cause mutations of Guanine (they convert Guanine to 8-Hydroxyguanine and other mutated products).

 

Chemical Data

Chemical Names

 2-amino-6-oxy purine; 6H-Purin-6-one, 2-amino-1,7-dihydro-

 2-Amino-1,7-dihydro-6H-purin-6-one

 2-Aminohypoxanthine

 2-Amino-6-hydroxypurine

 2-Amino-6-oxypurine

 

Molecular Formula

 C5H5N5O

 

 

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