Prostaglandin H2

Also known as:  Cyclic Endoperoxide;  PGH2

Prostaglandin H2 is a type of Series 2 Prostaglandin.

Eicosanoids

 Prostaglandin H2 functions primarily as an intermediate in the production of other Eicosanoids including:

 Hydroxyheptadecatrienoic Acid (HHT)

 Series 2 Prostaglandins including:

 Prostaglandin D2

 Prostaglandin E2

 Prostaglandin F2 alpha

 Prostaglandin I2

 Thromboxane A2 (the precursor for Thromboxane B2)

 View the Metabolic Pathway for Prostaglandin H2

Enzymes

 Prostaglandin D2 Synthase catalyzes the conversion of Prostaglandin H2 to Prostaglandin D2.

 The half-life of Prostaglandin H2 is less than five minutes.

Chemical Name

 15(S)-Hydroxy-(9-11)-peroxyprosta-5Z,13E-dienoic acid