Betaine-Homocysteine Methyltransferase

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  BHMT

 

Description

Betaine-Homocysteine Methyltransferase is an [1] Transmethylase Transferase Enzyme [E.C. No:  2.1.1.5].

 

BHMT may Enhance the Function of these Substances

Amino Acids

 BHMT catalyzes the endogenous production of Dimethyl Glycine (DMG) and Methionine from Homocysteine and Betaine.

 

BHMT may Inhibit these Toxic Substances

Amino Acids

 BHMT facilitates the detoxification of Homocysteine (it catalyzes the conversion of Homocysteine (with Betaine as a cofactor) to Dimethyl Glycine and Methionine).  [2]

 

These Substances may Enhance the Function of BHMT

Amino Acid Byproducts

 Betaine is a cofactor for BHMT and supplemental Betaine has been clearly shown to increase BHMT activity.  [3]

 

Minerals

 Zinc is a cofactor for BHMT.  [4]

 

Vitamins

 Choline may increase BHMT activity.  [5]

 

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