Pyruvate Carboxylase

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  Pyruvic Carboxylase

 

Description

Pyruvate Carboxylase is an Ligase Enzyme present in the Mitochondria of Cells.

 

Biological Function of Pyruvate Carboxylase

Metabolism

 Pyruvate Carboxylase catalyzes the conversion of Adenosine Triphosphate (ATP) + Pyruvic Acid toOxaloacetic Acid (i.e. it “feeds” Pyruvic Acid into the Krebs Cycle of Energy production) and Orthophosphate.

 

These Substances may Enhance the Function of Pyruvate Carboxylase

Minerals

 Manganese is an essential cofactor for the activation of Pyruvate Carboxylase.

 Zinc is a cofactor for Pyruvate Carboxylase.

 

Vitamins

 Biotin is an essential cofactor for the activation of Pyruvate Carboxylase.  [1]

 

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