Kynurenine

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  3-Anthraniloylalanine;  KYN

 

Description

Kynurenine is a metabolic byproduct of Tryptophan metabolism - chemically it is an Amino Acid.

 

Toxic Effects of Kynurenine

Metabolism

 Elevated Kynurenine levels are speculated to cause Cachexia (especially the Cachexia that afflicts persons with Acquired Immune Deficiency Syndrome).

 

These Substances may Enhance the Function of Kynurenine

Enzymes

 Tryptophan Pyrrolase catalyzes the conversion of Tryptophan to Kynurenine.

 

Kynurenine may Interfere with these Substances

Amino Acids

 Kynurenine competitively inhibits the transport of Tryptophan (by using the same transport carriers as Tryptophan).

 

Chemical Data

Molecular Formula

 C10H12N2O3

 

 

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