Agmatine

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Description

Agmatine is a metabolite of Arginine.  It is a naturally occurring Neurotransmitter that functions as an Alpha-2 Adrenergic Receptor Agonist.

 

Biological Function of Agmatine

Nervous System

 Agmatine stimulates Alpha-2 Adrenergic Receptors (and is therefore classified as an Alpha-2 Adrenergic Receptor Agonist).

 

Health Benefits of Agmatine

Nervous System

 Agmatine may reduce the symptoms of Alcohol Withdrawal Syndrome.  [1]

 Agmatine may alleviate Anxiety.  [2]

 Agmatine may alleviate Depression.  [3]

 

Agmatine may Counteract these Toxic Substances

Proteins

 Agmatine may inhibit the ability of Amyloid-Beta Protein to cause Memory impairment.  [4]

 

Recreational Drugs

 Agmatine may be useful for the treatment of Nicotine addiction.  [5]

 

Agmatine may Enhance the Function of these Substances

Hormones

 Agmatine may increase Luteinizing Hormone (LH) levels.

 

These Substances may Enhance the Function of Agmatine

Amino Acids

 Arginine is a precursor for the endogenous production of Agmatine.  [6]

 

Enzymes

 Arginine Decarboxylase catalyzes the conversion of Arginine to Agmatine.

 

Dosage Recommendations

 The usual therapeutic dosage of Agmatine is 500 – 1,000 mg per day.

 

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