Aging Process - Detrimental Consequences
Introduction
This section outlines the various detrimental physiological changes that occur during the progression of the Aging Process.
Detrimental Effects of the Aging Process
Cardiovascular System
The formation of atherosclerotic plaque that is implicit in Atherosclerosis may increase in tandem with the Aging Process.
The risk for Hypertension may increase in tandem with the progression of the Aging Process: [1]
Systolic Blood Pressure normally increases in tandem with the Aging Process.
The incidence of Hemorrhoids may increase in tandem with the progression of the Aging Process.
The incidence of Varicose Veins may increase in tandem with the progression of the Aging Process. [2]
Cells
The Aging Process is associated with a failure of damaged Cells to “kill themselves†via the process of (normal) Apoptosis and increased (abnormal) Apoptosis of non-damaged Cells. [3]
The integrity of the body’s Cell Membranes deteriorates in tandem with the progression of the Aging Process: [4]
The Phospholipids content of Cell Membranes declines in tandem with the progression of the Aging Process.
Damage to the Mitochondria of the body's Cells may be associated with the general slowdown that humans experience with the progression of the Aging Process: [5]
Errors that occur during the transcription of Deoxyribonucleic Acid (DNA) in association with the repair and replication of the body's Cells are implicated in the Aging Process. [6]
Free Radicals-induced damage (especially Superoxide Free Radicals and Hydrogen Peroxide Free Radicals) to the Mitochondria is speculated to be an important underlying cause of the Aging Process.
The Aging Process may cause the number of Melanocytes in the body to decrease by up to 20% each decade after the age of 30. [7]
The activity of Proteasomes may decline in tandem with the progression of the Aging Process. [8]
Digestive System
The incidence of Hypochlorhydria may increase in tandem with the Aging Process (due to the natural decline in the body's production of Hydrochloric Acid that occurs in tandem with the Aging Process).
Eyes/Vision
The risk of Age-Related Macular Degeneration (AMD) may increase in tandem with the Aging Process.
The incidence of Cataracts increases in tandem with the Aging Process.
The Lens of the Eye loses approximately 1% of its transparency each year in tandem with the progression of the Aging Process.
The Vitreous Humor of the Eyeball tends to contract, liquefy and separate from the Retina in tandem with the progression of the Aging Process.
Immune System
The risk of Autoimmune Diseases increases in tandem with the progression of the Aging Process. [9]
The general function of the Immune System may deteriorate in tandem with the Aging Process. [10]
The number of Langerhans Cells present in the Epidermis of the Skin declines in tandem with the progression of the Aging Process. [11]
The function of Macrophages deteriorates in tandem with the progression of the Aging Process. [12]
The function of Neutrophils deteriorates in tandem with the progression of the Aging Process.
The quantity and quality of T-Lymphocytes declines in tandem with the progression of the Aging Process. [13]
The Thymus Gland shrinks in tandem with the progression of the Aging Process. [14]
The risk of developing Prostate Cancer (for males) increases in tandem with the progression of the Aging Process.
The risk of developing Skin Cancer increases in tandem with the Aging Process.
Metabolism
The size of the Adipocytes (fat cells) in the Subcutaneous Tissue of the Skin increases in tandem with the progression of the Aging Process.
The number of Beta-3 Adrenergic Receptors declines in tandem with the progression of the Aging Process. [15]
The body’s Basal Metabolic Rate (BMR) declines after the age of 30 in tandem with the progression of the Aging Process - between the ages of 30 and 80, BMR declines by an average of 12%. [16]
The prevalence of Euthyroid Sick Syndrome increases in tandem with the progression of the Aging Process. [17]
Many of the ailments that become more prevalent with the progression of the Aging Process are initiated by excessive internal exposure to Free Radicals.
The risk of Hypothyroidism increases in tandem with the progression of the Aging Process.
The incidence of Insulin Resistance increases in tandem with the progression of the Aging Process. [18]
The risk of Obesity increases in tandem with the progression of the Aging Process. [19]
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