Vitamin B6 - Bioavailability
Description
This section describes the ease with which Vitamin B6 is assimilated into the body.
Bioavailability [1]
Dietary Vitamin B6 is readily absorbed by the Jejunum of the Small Intestine (by a non-saturable, passive process) and then phosphorylated to Pyridoxal-5-Phosphate by the enzyme Pyridoxal-5-Phosphatase.
Although supplemental oral Pyridoxal-5-Phosphate (P-5-P) is available commercially, the Phosphate molecule of P-5-P is removed from the ingested P-5P before it is absorbed, thus negating the claimed advantage of consuming supplemental Vitamin B6 in its Pyridoxal-5-Phosphate form:
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